Onderzoekers
prof.dr. P.A.J.M. Boon
neuroloog
Functie in Kempenhaeghe:
Directeur Onderzoek & Ontwikkeling, epileptoloog, voorzitter commissie Onderzoek & Ontwikkeling, coördinator onderzoeksgroep 'MRI', coordinator onderzoeksgroep 'Epilepsiechirurgie'
Specialisme:
Epileptologie
Subspecialisme:
- Klinische en experimentele epileptologie
- Prechirurgische evaluatie
- Neurostimulatie (Deep Brain Stimulation)
In Kempenhaeghe sinds: 1998
Gepromoveerd in: 1994
Titel proefschrift:
Refractory lesional epilepsy: clinical
and neurophysiological localisation
Overige informatie:
Hoofd afdeling neurologie en hoogleraar neurologie Universitair Ziekenhuis Gent
Wetenschappelijke publicaties
- Surgical successes and failures of invasive video-EEG monitoring in the presurgical evaluation of epilepsy. Van Loo P, Carrette E, Meurs A, Goossens L, Van Roost D, Vonck K, Boon P. Panminerva Med. 2011 Dec;53(4):227-40. PMID: 22146420
- Functional connectivity of dissociation in patients with psychogenic non-epileptic seizures. van der Kruijs SJ, Bodde NM, Vaessen MJ, Lazeron RH, Vonck K, Boon P, Hofman PA, Backes WH, Aldenkamp AP, Jansen JF. J Neurol Neurosurg Psychiatry. 2011 Nov 5. [Epub ahead of print] PMID: 22056967
- Patients with psychogenic non-epileptic seizures referred to a tertiary epilepsy centre: Patient characteristics in relation to diagnostic delay. Bodde NM, Lazeron RH, Wirken JM, van der Kruijs SJ, Aldenkamp AP, Boon PA. Clin Neurol Neurosurg. 2011 Nov 7. [Epub ahead of print] PMID: 22071205
- The cognitive effects of amygdalohippocampal deep brain stimulation in patients with temporal lobe epilepsy. Miatton M, Van Roost D, Thiery E, Carrette E, Van Dycke A, Vonck K, Meurs A, Vingerhoets G, Boon P. Epilepsy Behav. 2011 Oct 24. [Epub ahead of print] PMID: 22030536
- Development of an electronic decision tool to support appropriate treatment choice in adult patients with epilepsy - Epi-Scope(®). Legros B, Boon P, Ceulemans B, Coppens T, Geens K, Hauman H, Lagae L, Meurs A, Mol L, Ossemann M, van Rijckevorsel K, Van Zandijcke M, Vrielynck P, Wagemans D, Grisar T. Seizure. 2011 Oct 12. [Epub ahead of print] PMID: 22000707 [PubMed - as supplied by publisher]
- Antiepileptic drugs modulate P-glycoproteins in the brain: a mice study with (11)C-desmethylloperamide. Moerman L, Wyffels L, Slaets D, Raedt R, Boon P, De Vos F. Epilepsy Res. 2011 Mar;94(1-2):18-25. Epub 2011 Jan 31. PMID: 21277169
- Magnetoencephalography in epilepsy patients carrying a vagus nerve stimulator. Carrette E, De Tiège X, De Beeck MO, De Herdt V, Meurs A, Legros B, Raedt R, Deblaere K, Van Roost D, Bourguignon M, Goldman S, Boon P, Van Bogaert P, Vonck K. Epilepsy Res. 2011 Jan;93(1):44-52. Epub 2010 Dec 3. PMID: 21129918
- Local delivery strategies in epilepsy; a focus on adenosine. Van Dycke A, Raedt R, Vonck K, Boon P. Seizure. 2011 Apr 22. [Epub ahead of print] PMID: 21514852
- Antiepileptic drug treatment 2011; current limitations and future perspectives.Boon PA. Seizure. 2011 Apr 15. [Epub ahead of print] No abstract available. PMID: 21498088
- Automatic breath-to-breath analysis of nocturnal polysomnographic recordings.van Houdt PJ, Ossenblok PP, van Erp MG, Schreuder KE, Krijn RJ, Boon PA, Cluitmans PJ. Med Biol Eng Comput. 2011 Jul;49(7):819-30. Epub 2011 Mar 30. PMID: 21445719
- MMPI-II personality profiles of patients with psychogenic nonepileptic seizures.Bodde NM, Bartelet DC, Ploegmakers M, Lazeron RH, Aldenkamp AP, Boon PA. Epilepsy Behav. 2011 Apr;20(4):674-80. Epub 2011 Mar 29. PMID: 21450531 [PubMed - indexed for MEDLINE]
- Recording temporal lobe epileptic activity with MEG in a light-weight magnetic shield. Carrette E, Op de Beeck M, Bourguignon M, Boon P, Vonck K, Legros B, Goldman S, Van Bogaert P, De Tiège X. Seizure. 2011 Feb 25. [Epub ahead of print] PMID: 21354830 [PubMed - as supplied by publisher]
- Accurate epileptogenic focus localization through time-variant functional connectivity analysis of intracranial electroencephalographic signals. van Mierlo P, Carrette E, Hallez H, Vonck K, Van Roost D, Boon P, Staelens S. Neuroimage. 2011 Jun 1;56(3):1122-33. Epub 2011 Feb 18. PMID: 21316472 [PubMed - indexed for MEDLINE]
- Efficacy of vagus nerve stimulation for refractory epilepsy among patient subgroups: A re-analysis using the Engel classification. Wheeler M, De Herdt V, Vonck K, Gilbert K, Manem S, Mackenzie T, Jobst B, Roberts D, Williamson P, Van Roost D, Boon P, Thadani V. Seizure. 2011 May;20(4):331-5. Epub 2011 Jan 26. PMID: 21273097 [PubMed - indexed for MEDLINE]
- Vagus nerve stimulation and the postictal state. Vonck K, Raedt R, Boon P. Epilepsy Behav. 2010 Oct;19(2):182-5. Epub 2010 Aug 17. Review. PMID: 20724218 [PubMed - indexed for MEDLINE]
- Suppression of hippocampal epileptic seizures in the kainate rat by Poisson distributed stimulation. Wyckhuys T, Boon P, Raedt R, Van Nieuwenhuyse B, Vonck K, Wadman W. Epilepsia. 2010 Nov;51(11):2297-304. doi: 10.1111/j.1528-1167.2010.02750.x. Epub 2010 Oct 25. PMID: 20973781 [PubMed - indexed for MEDLINE]
- Suppression of hippocampal epileptic seizures in the kainate rat by Poisson distributed stimulation. Wyckhuys T, Boon P, Raedt R, Van Nieuwenhuyse B, Vonck K, Wadman W. Epilepsia. 2010 Nov;51(11):2297-304. doi: 10.1111/j.1528-1167.2010.02750.x. Epub 2010 Oct 25. PMID: 20973781 [PubMed - indexed for MEDLINE]
- Unconditioned adult-derived neurosphere cells mainly differentiate towards astrocytes upon transplantation in sclerotic rat hippocampus. Raedt R, Van Dycke A, Waeytens A, Wyckhuys T, Vonck K, Wadman W, Boon P. Epilepsy Res. 2009 Dec;87(2-3):148-59. Epub 2009 Sep 15. PMID: 19758788 [PubMed - indexed for MEDLINE]
- Comparison of analytical strategies for EEG-correlated fMRI data in patients with epilepsy. van Houdt PJ, de Munck JC, Zijlmans M, Huiskamp G, Leijten FS, Boon PA, Ossenblok PP. Magn Reson Imaging. 2010 Oct;28(8):1078-86. Epub 2010 May 14. PMID: 20471191 [PubMed - in process]
- Automatic detection of spike and wave discharges in the EEG of genetic absence epilepsy rats from Strasbourg. Van Hese P, Martens JP, Waterschoot L, Boon P, Lemahieu I. IEEE Trans Biomed Eng. 2009 Mar;56(3):706-17. Epub 2008 Nov 7. PMID: 19272875 [PubMed - indexed for MEDLINE]
- Continuous local intrahippocampal delivery of adenosine reduces seizure frequency in rats with spontaneous seizures. Van Dycke A, Raedt R, Dauwe I, Sante T, Wyckhuys T, Meurs A, Vonck K, Wadman W, Boon P. Epilepsia. 2010 Sep;51(9):1721-8. doi: 10.1111/j.1528-1167.2010.02700.x. Epub 2010 Aug 17. PMID: 20726873 [PubMed - in process]
- Astrocytes derived from fetal neural progenitor cells as a novel source for therapeutic adenosine delivery. Van Dycke A, Raedt R, Verstraete A, Theofilas P, Wadman W, Vonck K, Boison D, Boon P. Seizure. 2010 Sep;19(7):390-6. Epub 2010 Jun 17. PMID: 20688264 [PubMed - in process]
- Seizures in the intrahippocampal kainic acid epilepsy model: characterization using long-term video-EEG monitoring in the rat.Raedt Raedt R, Van Dycke A, Van Melkebeke D, De Smedt T, Claeys P, Wyckhuys T, Vonck K, Wadman W, Boon P. Acta Neurol Scand. 2009 May;119(5):293-303. PMID: 19388152 [PubMed - indexed for MEDLINE]
- Evolution in VNS therapy for refractory epilepsy, experience with Demipulse devices at Ghent University Hospital. El Tahry R, De Herdt V, Raedt R, Van Dycke A, Meurs A, Dewaele F, Boon P, Van Roost D, Vonck K. Seizure. 2010 Aug 10. [Epub ahead of print] PMID: 20702123 [PubMed - as supplied by publisher]
- Hippocampal activation during face-name associative memory encoding: blocked versus permuted design.De Vogelaere F, Santens P, Achten E, Boon P, Vingerhoets G. Neuroradiology. 2010 Jan;52(1):25-36. Epub 2009 May 6. PMID: 19418045 [PubMed - indexed for MEDLINE]
- Effects of vagus nerve stimulation on pro- and anti-inflammatory cytokine induction in patients with refractory epilepsy.12. De Herdt V, Bogaert S, Bracke KR, Raedt R, De Vos M, Vonck K, Boon P. Journal of Neuroimmunology 2009; 214(1-2): 104-108.
- Predictive factors for outcome of invasive video-EEG monitoring and subsequent resective surgery in patients with refractory epilepsy. Carrette E, Vonck K, De Herdt V, Van Dycke A, El Tahry R, Meurs A, Raedt R, Goossens L, Van Zandijcke M, Van Maele G, Thadani V, Wadman W, Van Roost D, Boon P. Clinical Neurology and Neurosurgery 2010; 112(2): 118-126.
- Hippocampal deep brain stimulation induces decreased rCBF in the hippocampal formation of the rat.Wyckhuys T, Staelens S, Van Nieuwenhuyse B, Deleye S, Hallez H, Vonck K, Raedt R, Wadman W, Boon P. Neuroimage. 2010 Aug 1;52(1):55-61. Epub 2010 Apr 13. PMID: 20394827 [PubMed - indexed for MEDLINE]
- Effect of levetiracetam on hippocampal protein expression and cell proliferation in rats. Paulson L, Persson A, Vonck K, Van Dycke A, Kuhn HG, Boon P, Ben-Menachem E, Raedt R. Epilepsy Res. 2010 Jun;90(1-2):110-20. PMID: 20435441 [PubMed - indexed for MEDLINE]
- Modulation of seizure threshold by vagus nerve stimulation in an animal model for motor seizures. De Herdt V, De Waele J, Raedt R, Wyckhuys T, El Tahry R, Vonck K, Wadman W, Boon P. Acta Neurol Scand. 2010 Apr;121(4):271-6. Epub 2009 Dec 10. PMID: 20003088 [PubMed - indexed for MEDLINE]
- Functional electrical stimulation of the left recurrent laryngeal nerve using a vagus nerve stimulator in a normal horse. Vanschandevijl K, Nollet H, Vonck K, Raedt R, Boon P, Roost D, Martens A, Deprez P. Vet J. 2010 Aug 17. [Epub ahead of print] PMID: 20724182 [PubMed - as supplied by publisher]
- Functional electrical stimulation of the left recurrent laryngeal nerve using a vagus nerve stimulator in a normal horse. Vanschandevijl K, Nollet H, Vonck K, Raedt R, Boon P, Roost D, Martens A, Deprez P. Vet J. 2010 Aug 17. [Epub ahead of print] PMID: 20724182 [PubMed - as supplied by publisher]
- EFNS guideline on the management of status epilepticus in adults.Meierkord H, Boon P, Engelsen B, Göcke K, Shorvon S, Tinuper P, Holtkamp M; European Federation of Neurological Societies. Eur J Neurol. 2010 Mar;17(3):348-55. Epub 2009 Dec 30. PMID: 20050893 [PubMed - indexed for MEDLINE]
- EFNS guideline on the management of status epilepticus in adults.Meierkord H, Boon P, Engelsen B, Göcke K, Shorvon S, Tinuper P, Holtkamp M; European Federation of Neurological Societies. Eur J Neurol. 2010 Mar;17(3):348-55. Epub 2009 Dec 30. PMID: 20050893 [PubMed - indexed for MEDLINE]
- MRS-lateralisation index in patients with epilepsy and focal cortical dysplasia or a MEG-focus using bilateral single voxels.Colon AJ, Hofman P, Ossenblok PP, Jansen JF, Ter Beek LC, Berting R, Stam CJ, Boon P. Epilepsy Res. 2010 Mar;89(1):148-53. Epub 2009 Dec 21. PMID: 20022471
- Correction for pulse height variability reduces physiological noise in functional MRI when studying spontaneous brain activity. van Houdt PJ, Ossenblok PP, Boon PA, Leijten FS, Velis DN, Stam CJ, de Munck JC. Hum Brain Mapp. 2010 Feb;31(2):311-25. PMID: 19662656 [PubMed - indexed for MEDLINE]
- Comparison of hippocampal Deep Brain Stimulation with high (130Hz) and low frequency (5Hz) on afterdischarges in kindled rats. Wyckhuys T, Raedt R, Vonck K, Wadman W, Boon P. Epilepsy Res. 2010 Feb;88(2-3):239-46. Epub 2009 Dec 30. PMID: 20044240 [PubMed - indexed for MEDLINE]
- Effect of levetiracetam on hippocampal protein expression and cell proliferation in rats. Paulson L, Persson A, Vonck K, Van Dycke A, Kuhn HG, Boon P, Ben-Menachem E, Raedt R. Epilepsy Res. 2010 Apr 30. [Epub ahead of print] PMID: 20435441 [PubMed - as supplied by publisher]
- Use of routine MEG in the primary diagnostic process of epilepsy. Colon AJ, Ossenblok P, Nieuwenhuis L, Stam KJ, Boon P. J Clin Neurophysiol. 2009 Oct;26(5):326-32. PMID: 19752741 [PubMed - indexed for MEDLINE]
- Use of routine MEG in the primary diagnostic process of epilepsy. Colon AJ, Ossenblok P, Nieuwenhuis L, Stam KJ, Boon P. J Clin Neurophysiol. 2009 Oct;26(5):326-32. PMID: 19752741 [PubMed - indexed for MEDLINE]
- Psychogenic non-epileptic seizures--definition, etiology, treatment and prognostic issues: a critical review. Bodde NM, Brooks JL, Baker GA, Boon PA, Hendriksen JG, Mulder OG, Aldenkamp AP. Seizure. 2009 Oct;18(8):543-53. Epub 2009 Aug 13. Review. PMID: 19682927 [PubMed - indexed for MEDLINE]
- Opinion of Belgian neurologists on antiepileptic drug treatment in 2006: Belgian study on epilepsy treatment (BESET-2). Legros B, Boon P, De Jonghe P, Sadzot B, Van Rijckevorsel K, Schmedding E. Acta Neurol Scand. 2009 Dec;120(6):402-10. Epub 2009 Oct 5. PMID: 19804468 [PubMed - indexed for MEDLINE]
- Opinion of Belgian neurologists on antiepileptic drug treatment in 2006: Belgian study on epilepsy treatment (BESET-2). Legros B, Boon P, De Jonghe P, Sadzot B, Van Rijckevorsel K, Schmedding E. Acta Neurol Scand. 2009 Dec;120(6):402-10. Epub 2009 Oct 5. PMID: 19804468 [PubMed - indexed for MEDLINE]
- Opinion of Belgian neurologists on antiepileptic drug treatment in 2006: Belgian study on epilepsy treatment (BESET-2). Legros B, Boon P, De Jonghe P, Sadzot B, Van Rijckevorsel K, Schmedding E. Acta Neurol Scand. 2009 Dec;120(6):402-10. Epub 2009 Oct 5. PMID: 19804468 [PubMed - indexed for MEDLINE]
- Progressive myoclonic epilepsy as an adult-onset manifestation of Leigh syndrome due to m.14487T>C. Dermaut B, Seneca S, Dom L, Smets K, Ceulemans L, Smet J, De Paepe B, Tousseyn S, Weckhuysen S, Gewillig M, Pals P, Parizel P, De Bleecker JL, Boon P, De Meirleir L, De Jonghe P, Van Coster R, Van Paesschen W, Santens P. J Neurol Neurosurg Psychiatry. 2010 Jan;81(1):90-3. PMID: 20019223 [PubMed - in process]
- Opinion of Belgian neurologists on antiepileptic drug treatment in 2006: Belgian study on epilepsy treatment (BESET-2). Legros B, Boon P, De Jonghe P, Sadzot B, Van Rijckevorsel K, Schmedding E. Acta Neurol Scand. 2009 Oct 5. [Epub ahead of print] PMID: 19804468 [PubMed - as supplied by publisher]
- Opinion of Belgian neurologists on antiepileptic drug treatment in 2006: Belgian study on epilepsy treatment (BESET-2). Legros B, Boon P, De Jonghe P, Sadzot B, Van Rijckevorsel K, Schmedding E. Acta Neurol Scand. 2009 Oct 5. [Epub ahead of print] PMID: 19804468 [PubMed - as supplied by publisher]
- Deep brain stimulation for epilepsy: knowledge gained from experimental animal models. Wyckhuys T, Geerts PJ, Raedt R, Vonck K, Wadman W, Boon P. Acta Neurol Belg. 2009 Jun;109(2):63-80. Review. PMID: 19681438 [PubMed - indexed for MEDLINE]
- Deep brain stimulation for epilepsy: knowledge gained from experimental animal models. Wyckhuys T, Geerts PJ, Raedt R, Vonck K, Wadman W, Boon P. Acta Neurol Belg. 2009 Jun;109(2):63-80. Review. PMID: 19681438 [PubMed - indexed for MEDLINE]
- Deep brain stimulation for epilepsy: knowledge gained from experimental animal models. Wyckhuys T, Geerts PJ, Raedt R, Vonck K, Wadman W, Boon P. Acta Neurol Belg. 2009 Jun;109(2):63-80. Review. PMID: 19681438 [PubMed - indexed for MEDLINE]
- Deep brain stimulation for epilepsy: knowledge gained from experimental animal models. Wyckhuys T, Geerts PJ, Raedt R, Vonck K, Wadman W, Boon P. Acta Neurol Belg. 2009 Jun;109(2):63-80. Review. PMID: 19681438 [PubMed - indexed for MEDLINE]
- Correction for pulse height variability reduces physiological noise in functional MRI when studying spontaneous brain activity. van Houdt PJ, Ossenblok PP, Boon PA, Leijten FS, Velis DN, Stam CJ, de Munck JC. Hum Brain Mapp. 2009 Aug 6. [Epub ahead of print] PMID: 19662656 [PubMed - as supplied by publisher]
- Increased rat serum corticosterone suggests immunomodulation by stimulation of the vagal nerve. De Herdt V, Puimege L, De Waele J, Raedt R, Wyckhuys T, El Tahry R, Libert C, Wadman W, Boon P, Vonck K. J Neuroimmunol. 2009 Jul 25;212(1-2):102-5. Epub 2009 May 14. PMID: 19446345 [PubMed - indexed for MEDLINE]
- Increased rat serum corticosterone suggests immunomodulation by stimulation of the vagal nerve. De Herdt V, Puimege L, De Waele J, Raedt R, Wyckhuys T, El Tahry R, Libert C, Wadman W, Boon P, Vonck K. J Neuroimmunol. 2009 Jul 25;212(1-2):102-5. Epub 2009 May 14. PMID: 19446345 [PubMed - indexed for MEDLINE]
- Vagus nerve stimulation for refractory status epilepticus De Herdt V, Waterschoot L, Vonck K, Dermaut B, Verhelst H, Van Coster R, De Jaeger A, Van Roost D, Boon P. Eur J Paediatr Neurol. 2009 May;13(3):286-9. Epub 2008 Jun 27. PMID: 18585939 [PubMed - indexed for MEDLINE]
- Electrical stimulation for the treatment of epilepsy Boon P, Raedt R, de Herdt V, Wyckhuys T, Vonck K. Neurotherapeutics. 2009 Apr;6(2):218-27. Review. PMID: 19332313 [PubMed - indexed for MEDLINE]
- Vagal nerve stimulation--a 15-year survey of an established treatment modality in epilepsy surgery. Vonck K, De Herdt V, Boon P. Adv Tech Stand Neurosurg. 2009;34:111-46. Review. PMID: 19368083 [PubMed - indexed for MEDLINE]
- Vagal nerve stimulation--a 15-year survey of an established treatment modality in epilepsy surgery. Vonck K, De Herdt V, Boon P. Adv Tech Stand Neurosurg. 2009;34:111-46. Review. PMID: 19368083 [PubMed - indexed for MEDLINE]
- Vagal nerve stimulation--a 15-year survey of an established treatment modality in epilepsy surgery. Vonck K, De Herdt V, Boon P. Adv Tech Stand Neurosurg. 2009;34:111-46. Review. PMID: 19368083 [PubMed - indexed for MEDLINE]
- Vagal nerve stimulation--a 15-year survey of an established treatment modality in epilepsy surgery. Vonck K, De Herdt V, Boon P. Adv Tech Stand Neurosurg. 2009;34:111-46. Review. PMID: 19368083 [PubMed - indexed for MEDLINE]
- An investigation of the phase locking index for measuring of interdependency of cortical source signals recorded in the EEG Sazonov AV, Ho CK, Bergmans JW, Arends JB, Griep PA, Verbitskiy EA, Cluitmans PJ, Boon PA. Biol Cybern. 2009 Feb;100(2):129-46. Epub 2009 Jan 17. PMID: 19152066 [PubMed - indexed for MEDLINE]
- An investigation of the phase locking index for measuring of interdependency of cortical source signals recorded in the EEG Sazonov AV, Ho CK, Bergmans JW, Arends JB, Griep PA, Verbitskiy EA, Cluitmans PJ, Boon PA. Biol Cybern. 2009 Feb;100(2):129-46. Epub 2009 Jan 17. PMID: 19152066 [PubMed - indexed for MEDLINE]
- Thalamic and limbic involvement in the mechanism of action of vagus nerve stimulation, a SPECT study Vonck K, De Herdt V, Bosman T, Dedeurwaerdere S, Van Laere K, Boon P. Seizure. 2008 Dec;17(8):699-706. Epub 2008 Jun 16. PMID: 18556220 [PubMed - indexed for MEDLINE]
- Recommendations for the treatment of epilepsies in general practice in Belgium. Boon P, Engelborghs S, Hauman H, Jansen A, Lagae L, Legros B, Ossemann M, Sadzot B, Urbain E, van Rijckevorsel K. Acta Neurol Belg. 2008 Dec;108(4):118-30. PMID: 19239040 [PubMed - in process]
- Automatic Detection of Spike and Wave Discharges in the EEG of Genetic Absence Epilepsy Rats From Strasbourg. Van Hese P, Martens JP, Waterschoot L, Boon P, Lemahieu I. IEEE Trans Biomed Eng. 2008 Nov 7. [Epub ahead of print] PMID: 19272875 [PubMed - as supplied by publisher]
- Contribution of magnetic source imaging to the presurgical work-up of patients with refractory partial epilepsy. De Tiège X, Op de Beeck M, Bourguignon M, Legros B, Carette E, Vonck K, Boon P, Baleriaux D, Goldman S, Van Bogaert P. JBR-BTR. 2008 Nov-Dec;91(6):249-53. Review. PMID: 19202999 [PubMed - indexed for MEDLINE]
- Psychogenic non-epileptic seizures--diagnostic issues: a critical review. Bodde NM, Brooks JL, Baker GA, Boon PA, Hendriksen JG, Aldenkamp AP. Clin Neurol Neurosurg. 2009 Jan;111(1):1-9. Epub 2008 Nov 18. Review. PMID: 19019531 [PubMed - indexed for MEDLINE]
- An investigation of the phase locking index for measuring of interdependency of cortical source signals recorded in the EEG. Sazonov AV, Ho CK, Bergmans JW, Arends JB, Griep PA, Verbitskiy EA, Cluitmans PJ, Boon PA. Biol Cybern. 2009 Jan 17. [Epub ahead of print] PMID: 19152066 [PubMed - as supplied by publisher]
- An investigation of the phase locking index for measuring of interdependency of cortical source signals recorded in the EEG. Sazonov AV, Ho CK, Bergmans JW, Arends JB, Griep PA, Verbitskiy EA, Cluitmans PJ, Boon PA. Biol Cybern. 2009 Jan 17. [Epub ahead of print] PMID: 19152066 [PubMed - as supplied by publisher]
- Psychogenic non-epileptic seizures-Diagnostic issues: A critical review. Clin Neurol Neurosurg. 2008 Nov 17; [Epub ahead of print] PMID: 19019531 [PubMed - as supplied by publisher]Bodde NM, Brooks JL, Baker GA, Boon PA, Hendriksen JG, Aldenkamp AP.
- A pilot trial with modified Atkins' diet in adult patients with refractory epilepsy. Clin Neurol Neurosurg. 2008 Sep;110(8):797-803. Epub 2008 Jun 24. PMID: 18572306 [PubMed - indexed for MEDLINE]Carrette E, Vonck K, de Herdt V, Dewaele I, Raedt R, Goossens L, Van Zandijcke M, Wadman W, Thadani V, Boon P.
- Impact of reimbursement restrictions on the choice of antiepileptic drugs: Belgian Study on Epilepsy Treatment (BESET). Seizure. 2008 Jun;17(4):350-7. Epub 2008 Jan 18. PMID: 18203628 [PubMed - indexed for MEDLINE]Boon P, Dejonghe P, Legros B, Sadzot B, van Rijckevorsel K, Schmedding E.
- Thalamic and limbic involvement in the mechanism of action of vagus nerve stimulation, a SPECT study. Seizure. 2008 Jun 13; [Epub ahead of print] PMID: 18556220 Vonck K, De Herdt V, Bosman T, Dedeurwaerdere S, Van Laere K, Boon P.
- Levetiracetam and bleeding disorders. Acta Neurol Belg. 2007 Dec;107(4):97-102. PMID: 18416281 Boon P, Hulhoven R, Offner F.
- Analysis of the phase locking index for measuring of interdependency of cortical signals recorded in the EEG. Conf Proc IEEE Eng Med Biol Soc. 2007;2007:1985-91. PMID: 18002374 Sazonov AV, Ho CK, Bergmans JW, Arends JB, Griep PA, Verbitskiy EA, Cluitmans PJ, Boon PA.
- Levetiracetam and bleeding disorders. Acta Neurol Belg. 2007 Dec;107(4):97-102. PMID: 18416281
- Vallenga D, Grypdonck MH, Tan FI, Lendemeijer BH, Boon PA. Improving decision-making in caring for people with epilepsy and intellectual disability: an action research project. Vallenga D, Grypdonck MH, Tan FI, Lendemeijer BH, Boon PA. J Adv Nurs. 2008 Feb;61(3):261-72. PMID: 18197861 [PubMed - in process]
- Impact of reimbursement restrictions on the choice of antiepileptic drugs: Belgian Study on Epilepsy Treatment (BESET). Boon P, Dejonghe P, Legros B, Sadzot B, van Rijckevorsel K, Schmedding E. Seizure. 2008 Jan 17; [Epub ahead of print] PMID: 18203628 [PubMed - as supplied by publisher]
- Impact of reimbursement restrictions on the choice of antiepileptic drugs: Belgian Study on Epilepsy Treatment (BESET). Seizure. 2008 Jan 17; [Epub ahead of print] PMID: 18203628 Boon P, Dejonghe P, Legros B, Sadzot B, van Rijckevorsel K, Schmedding E.
- Improving decision-making in caring for people with epilepsy and intellectual disability: an action research project. J Adv Nurs. 2008 Feb;61(3):261-272. PMID: 18197861 Vallenga D, Grypdonck MH, Tan FI, Lendemeijer BH, Boon PA.
- EEG source localization of the epileptogenic focus in patients with refractory temporal lobe epilepsy, dipole modelling revisited. Verhellen E, Boon P.
- Analysis of the phase locking index for measuring of interdependency of cortical signals recorded in the EEG - Sazonov AV, Ho CK, Bergmans JW, Arends JB, Griep PA, Verbitskiy EA, Cluitmans PJ, Boon PA.
- Clinical experience with vagus nerve stimulation and deep brain stimulation in epilepsy. Acta Neurochir Suppl. 2007;97(Pt 2):273-80. PMID: 17691313 [PubMed - in process]: Boon P, De Herdt V, Vonck K, Van Roost D.
- Anatomical and physiological basis and mechanism of action of neurostimulation for epilepsy. Acta Neurochir Suppl. 2007;97(Pt 2):321-8. PMID: 17691318 [PubMed - in process]Vonck K, Boon P, Van Roost D.
- Neurosurgical aspects of temporal deep brain stimulation for epilepsy. Acta Neurochir Suppl. 2007;97(Pt 2):333-6. PMID: 17691320 [PubMed - in process]Van Roost D, Boon P, Vonck K, Caemaert J.
- Deep brain stimulation in patients with refractory temporal lobe epilepsy. Epilepsia. 2007 Aug;48(8):1551-60. PMID: 17726798 [PubMed - in process] Boon P, Vonck K, De Herdt V, Van Dycke A, Goethals M, Goossens L, Van Zandijcke M, De Smedt T, Dewaele I, Achten R, Wadman W, Dewaele F, Caemaert J, Van Roost D.
- Analysis of Initial Slow Waves (ISWs) at the Seizure Onset in Patients with Drug Resistant Temporal Lobe Epilepsy. Epilepsia. 2007 Jun 9; [Epub ahead of print] PMID: 17559569 [PubMed - as supplied by publisher] Bragin A, Claeys P, Vonck K, Van Roost D, Wilson C, Boon P, Engel J.
- Serial day rapid kindling is an effective tool in screening the anti-epileptic properties of topiramate. Seizure. 2007 Jun 6; [Epub ahead of print] PMID: 17560133 [PubMed - as supplied by publisher] De Smedt T, De Rouck S, Raedt R, Wyckhuys T, Waterschoot L, De Herdt V, Van Dycke A, Tahry RE, Vonck K, Boon P.
- Cell therapy in models for temporal lobe epilepsy. Seizure. 2007 Jun 11; [Epub ahead of print] PMID: 17566770 [PubMed - as supplied by publisher] Raedt R, Van Dycke A, Vonck K, Boon P.
- Factors involved in the long-term prognosis of psychogenic nonepileptic seizures. J Psychosom Res. 2007 May;62(5):545-51. PMID: 17467409 [PubMed - in process]Bodde NM, Janssen AM, Theuns C, Vanhoutvin JF, Boon PA, Aldenkamp AP.
- Levetiracetam: the profile of a novel anticonvulsant drug-part I: preclinical data. CNS Drug Rev. 2007 Spring;13(1):43-56. PMID: 17461889 [PubMed - in process] De Smedt T, Raedt R, Vonck K, Boon P.
- Levetiracetam: Part II, the Clinical Profile of a Novel Anticonvulsant Drug. CNS Drug Rev. 2007 Spring;13(1):57-78. PMID: 17461890 [PubMed - in process]De Smedt T, Raedt R, Vonck K, Boon P.
- High Frequency Deep Brain Stimulation in the Hippocampus Modifies Seizure Characteristics in Kindled Rats. Epilepsia. 2007 Mar 22; [Epub ahead of print] PMID: 17381435 [PubMed - as supplied by publisher] Wyckhuys T, De Smedt T, Claeys P, Raedt R, Waterschoot L, Vonck K, Broecke CV, Mabilde C, Leybaert L, Wadman W, Boon P.
- Vagus nerve stimulation for refractory epilepsy: A Belgian multicenter study. Eur J Paediatr Neurol. 2007 Mar 27; [Epub ahead of print] PMID: 17395507 [PubMed - as supplied by publisher De Herdt V, Boon P, Ceulemans B, Hauman H, Lagae L, Legros B, Sadzot B, Van Bogaert P, van Rijckevorsel K, Verhelst H, Vonck K.
- Legros B, Boon P, Dejonghe P, Sadzot B, Van Rijckevorsel K, Schmedding E. - Opinion of Belgian neurologists on antiepileptic drugs: Belgian Study on Epilepsy Treatment (BESET). Acta Neurol Scand. 2007 Feb;115(2):97-103. PMID: 17212612 [PubMed - in process]
- Boon PA[Electrode grids are available for the selection of patients with refractory epilepsy for epilepsy surgery] Ned Tijdschr Geneeskd. 2006 Oct 28;150(43):2353-4. Dutch. PMID: 17100124
- van Rijckevorsel K, Boon P, Hauman H, Legros B, Ossemann M, Sadzot B, Schmedding E, van Zandijcke M. Standards of care for non-convulsive status epilepticus: Belgian consensus recommendations. Acta Neurol Belg. 2006 Sep;106(3):117-24. PMID: 17091614 [PubMed - in process]
- Differentiation assays of bone marrow-derived Multipotent Adult Progenitor Cell (MAPC)-like cells towards neural cells cannot depend on morphology and a limited set of neural markers. Exp Neurol. 2006 Oct 30; [Epub ahead of print] PMID: 17078948 [PubMed - as supplied by publisher]
- Lambrechts DA, Sadzot B, van Paesschen W, van Leusden JA, Carpay J, Bourgeois P, Urbain E, Boon PA. Efficacy and safety of levetiracetam in clinical practice: Results of the SKATEtrade mark trial from Belgium and The Netherlands. Seizure. 2006 Aug 5;
- Dedeurwaerdere S, Vonck K, De Herdt V, Waterschoot L, De Smedt T, Raedt R, Wyckhuys T, Legros B, Van Hese P, Van Laere K, Delbeke J, Wadman W, Boon P. Neuromodulation with levetiracetam and vagus nerve stimulation in experimental animal models of epilepsy. Acta Neurol Belg. 2006 Jun;106(2):91-7.
- Vallenga D, Grypdonck MH, Tan FI, Lendemeijer BH, Boon PA. Decision-making about risk in people with epilepsy and intellectual disability. J Adv Nurs. 2006 Jun;54(5):602-11.
- Meierkord H, Boon P, Engelsen B, Gocke K, Shorvon S, Tinuper P, Holtkamp M. EFNS guideline on the management of status epilepticus. Eur J Neurol. 2006 May;13(5):445-50.
- de Haan GJ, Pinto D, Carton D, Bader A, Witte J, Peters E, van Erp G, Vandereyken W, Boezeman E, Wapenaar MC, Boon P, Halley D, Koeleman BP, Lindhout D. A Novel Splicing Mutation in KCNQ2 in a Multigenerational Family with BFNC Followed for 25 Years.Epilepsia. 2006 May;47(5):851-9.
- Dedeurwaerdere S, Gilby K, Vonck K, Delbeke J, Boon P, McIntyre D. Vagus nerve stimulation does not affect spatial memory in fast rats, but has both anti-convulsive and pro-convulsive effects on amygdala-kindled seizures. Neuroscience. 2006 Apr 27;
- Boon P, Moors I, De Herdt V, Vonck K. Vagus nerve stimulation and cognition. Seizure. 2006 Apr 29;
- Backes WH, Deblaere K, Vonck K, Kessels AG, Boon P, Hofman P, Wilmink JT, Vingerhoets G, Boon PA, Achten R, Vermeulen J, Aldenkamp AP. Language activation distributions revealed by fMRI in post-operative epilepsy patients: differences between left- and right-sided resections. Epilepsy Res. 2005 Aug-Sep;66(1-3):1-12.
- De Smedt T, Vonck K, Raedt R, Dedeurwaerdere S, Claeys P, Legros B, Wyckhuys T, Wadman W, Boon P. Rapid kindling in preclinical anti-epileptic drug development: the effect of levetiracetam. Epilepsy Res. 2005 Dec;67(3):109-16. Epub 2005 Nov 9.
- Vingerhoets G, Miatton M, Vonck K, Seurinck R, Boon P. Memory performance during the intracarotid amobarbital procedure and neuropsychological assessment in medial temporal lobe epilepsy: The limits of material specificity. Epilepsy Behav. 2006 Jan 10;
- Verhelst H, Boon P, Buyse G, Ceulemans B, D'Hooghe M, Meirleir LD, Hasaerts D, Jansen A, Lagae L, Meurs A, Coster RV, Vonck K. Steroids in intractable childhood epilepsy: clinical experience and review of the literature. Seizure. 2005 Sep;14(6):412-21.
- van Rijckevorsel K, Boon P, Hauman H, Legros B, Ossemanns M, Sadzot B, Schmedding E, van Zandijcke M. Standards of care for adults with convulsive status epilepticus: Belgian consensus recommendations. Acta Neurol Belg. 2005 Sep;105(3):111-8. Review.
- Raedt R, Boon P. Cell therapy for neurological disorders: a comprehensive review. Acta Neurol Belg. 2005 Sep;105(3):158-70. Review.
- Dedeurwaerdere S, Cornelissen B, Van Laere K, Vonck K, Achten E, Slegers G, Boon P. Small animal positron emission tomography during vagus nerve stimulation in rats: A pilot study. Epilepsy Res. 2005 Nov 8;
- De Smedt T, Vonck K, Raedt R, Dedeurwaerdere S, Claeys P, Legros B, Wyckhuys T, Wadman W, Boon P. Rapid kindling in preclinical anti-epileptic drug development: The effect of levetiracetam. Epilepsy Res. 2005 Nov 7;
- Lateralized anterior mesiotemporal lobe activation: semirandom functional MR imaging encoding paradigm in patients with temporal lobe epilepsy--initial experience. Radiology. 2005 Sep;236(3):996-1003.
- Pinto D, de Haan GJ, Carton D, Bader A, Witte J, Peters E, van Erp MG, Vandereyken W, Boezeman EH, Boon P, Halley DJ, Koeleman BP, Lindhout D. Disease: Benign neonatal familial convulsion. Hum Genet. 2005 Jul;117(2-3):300. No abstract available.
- Dedeurwaerdere S, Vonck K, Van Hese P, Wadman W, Boon P. The acute and chronic effect of vagus nerve stimulation in genetic absence epilepsy rats from Strasbourg (GAERS). Epilepsia. 2005;46 Suppl 5:94-7
- Vonck K, Boon P, Claeys P, Dedeurwaerdere S, Achten R, Van Roost D. Long-term deep brain stimulation for refractory temporal lobe epilepsy. Epilepsia. 2005;46 Suppl 5:98-9. No abstract available
- Verhelst H, Boon P, Buyse G, Ceulemans B, D'Hooghe M, Meirleir LD, Hasaerts D, Jansen A, Lagae L, Meurs A, Coster RV, Vonck K. Steroids in intractable childhood epilepsy: Clinical experience and review of the literature. Seizure. 2005 Aug 5
- Dedeurwaerdere S, Boon P, De Smedt T, Claeys P, Raedt R, Bosman T, Van Hese P, Van Maele G, Vonck K. Chronic levetiracetam treatment early in life decreases epileptiform events in young GAERS, but does not prevent the expression of spike and wave discharges during adulthood. Seizure. 2005 Aug 8
- Backes WH, Deblaere K, Vonck K, Kessels AG, Boon P, Hofman P, Wilmink JT, Vingerhoets G, Boon PA, Achten R, Vermeulen J, Aldenkamp AP. Language activation distributions revealed by fMRI in post-operative epilepsy patients: Differences between left- and right-sided resections. Epilepsy Res. 2005 Aug 20
- Deblaere K, Backes WH, Tieleman A, Vandemaele P, Defreyne L, Vonck K, Hofman P, Boon P, Vermeulen J, Wilmink J, Aldenkamp A, Boon PA, Vingerhoets G, Achten E. Lateralized Anterior Mesiotemporal Lobe Activation: Semirandom Functional MR Imaging Encoding Paradigm in Patients with Temporal Lobe Epilepsy--Initial Experience. Radiology. 2005 Sep;236(3):996-1003.
- Dedeurwaerdere S, Vonck K, Van Hese P, Wadman W, Boon P. The Acute and Chronic Effect of Vagus Nerve Stimulation in Genetic Absence Epilepsy Rats from Strasbourg (GAERS). Epilepsia. 2005;46 Suppl 5:94-7.
- Vonck K, Boon P, Claeys P, Dedeurwaerdere S, Achten R, Van Roost D. Long-term Deep Brain Stimulation for Refractory Temporal Lobe Epilepsy. Epilepsia. 2005;46 Suppl 5:98-9.
- Vonck K, Dedeurwaerdere S, De Groote L, Thadani V, Claeys P, Gossiaux F, Van Roost D, Boon P. Generator replacement in epilepsy patients treated with vagus nerve stimulation. Seizure. 2005 Mar;14(2):89-99.
- SC Ebus, HJ Majoie, JB Arends, PJ Boon.Can spikes predict seizure frequency? Results of a pilot study in severe childhood epilepsies treated with vagus nerve stimulation. Seizure. 2004 Oct;13(7):494-8.
- Vonck K, Boon P, Achten E, De Reuck J, Caemaert J. Long-term amygdalohippocampal stimulation for refractory temporal lobe epilepsy. Annals of Neurology 2002; 52:556-565.
- Vonck K., Van Laere K., Dedeurwaedere S., Caemaert J., De Reuck J., Boon P.A.J.M. The mechanism of action of vagus nerve stimulation for refractory epilepsy, the current status.. J Clin Neurophysiol 2001;18:394-401
- Vonck K., Boon P.A.J.M., Van Laere K., D’Have M., Vandekerckhove T., O’Connor S., Brans B., Dierckx R., De Reuck J. Acute single photon emission computed tomographic study of vagus nerve stimulation in refractory epilepsy. Epilepsia 2000;41:601-609.
- Vingerhoets G, Deblaere K., Backes WH, Achten E, Boon P, Boon PA, Hofman P, Vermeulen J, Vonck K, Wilmink J, Aldenkamp AP. Lessons for neuropsychology from functional MRI in patients with epilepsy. Epilepsy & Behaviour 2004; 5(S1):81-89.
- Van Rijckevorsel K., Boon P.A.J.M. The ”number needed to treat”with Levetiracetam (LEV): comparison with other antiepileptic drugs. Seizure 2001;10:235-236
- Vanrumste B, Van Hoey G, Van de Walle R, D’Have M, Lemahieu I, Boon P. Comparison of performance of spherical and realistic head models in dipole localization from noisy EEG. Medical Engineering & Physics 2002; 24:403-418.
- Vanrumste B., Van Hoey G., Van De Walle R., D'Havè M., Lemahieu I., Boon P.A.J.M. The Validation of the Finite Difference Method and Reciprocity for Solving the Inverse Problem in EEG Dipole Source Analysis. Brain Topography 2001;14:83-92
- Vanrumste B., Van Hoey G., Van De Walle R., D’Have M., Lemahieu I., Mahieu E., Boon P.A.J.M. Dipole location errors in electroencephalogram source analysis due to volume conductor model errors. Med. Biol. Eng. Comput 2000;38:528-534
- Van Laere K., Vonck K., Boon P.A.J.M., Vandekerckhove T., Brans B., Dierckx R. Vagal nerve stimulation in refractory epilepsy: a single-photon emission computed tomography activation study. J. Nucl. Med 2000;41:1145-1154
- Van Hoey G., De Clercq J., Vanrumste B., Van De Walle R., Lemahieu I., D’Have M., Boon P.A.J.M. EEG Dipole Source Localization Using Artificial Neural Networks. Phys. Med. Biol. 2000;45:997-1011
- Van Hoey G., Vanrumste B., D'Have M., Van De Walle R., Lemahieu I., Boon P.A.J.M. The Influence of Measurement Noise and Electrode Mislocalisation on EEG Dipole Source Localization. Med. Biol. Comput. Eng. 2000;38:287-296
- Tallis R, Boon P, Perucca E, Stephen L. Epilepsy in elderly people: management issues. Epileptic Disorders 2002; 4(suppl.2):33-40.
- Sijbers J., Vanrumste B., Van Hoey G., Boon P.A.J.M., Verhoye M., Van Der Linden A., Van Dyck D. Automatic localization of EEG electrode markers with 3D-MR data. Magnetic Resonance Imaging 2000;18:485-490
- Le van Quen M., Martinerie J., Navarro V., Boon P.A.J.M., D’Have M., Adam C., Renault B., Varela F., Baulac M. Anticipation of epileptic seizures from standard EEG recordings. Lancet 2001;357:183-188
- Lesaffre E., Boon P.A.J.M., Pledger GW. The value of the number-needed-to-treat method in antiepileptic drug trials. Epilepsia 2000;41:440-446
- Laere van K, Vonck, Boon P, Versijpt J, Dierckx R. Perfusion SPECT changes after acute and chronic vagus nerve stimulation in relation to prestimulus condition and long-term clinical efficacy. Journal of Nuclear Medicine 2002; 43:733-744
- Heaney D.C., Shorvon S.D., Sander J.W., Boon P.A.J.M., et al. Cost minimisation analysis of anti-epileptic drugs in newly diagnosed epilepsy in 12 european countries. Epilepsia 2000;41(suppl 5):37-44
- Goethals I, Van De Wiele C, Boon P, Dierckx R. Is central benzodiazepine receptor imaging useful for identification of epileptogenic foci in localization-related epilepsies? European Journal of Nuclear Medicine and Molecular Imaging 2003; 30:325-328.
- Deherdt, V, Boon P, Goossens L, Vonck K, Nieuwenhuis L, Paemeleire K, Meire V, Michielsen G, Baert E, Van Roost D. Are psychotic symptoms related to vagus nerve stimualtion in epilepsy patients? Acta Neurologica Belgica 2003; 103:170-175.
- Deblaere K, Backes WH, Hofman P, Vandemaele P, Boon PA, Vonck K, Boon P, Troost J, Vermeulen J, Wilmink J, Achten E, Aldenkamp AP. Developing a comprehensive presurgical functional MRI protocol for patients with intractable temporal lobe epilepsy. Neuroradiology 2002; 44(8):667-673.
- Boon P. Refractory Epilepsy; European White Paper on Epilepsy Epilepsia 2003; 44(suppl. 6):81-82.
- Boon P, Vanrumste B, Van Hoey G, Vonck K, Van Walleghem P, Caemaert J, Achten E, De Reuck J. Ictal source localization in presurgical patients with refractory epilepsy. Journal of Clinical Neurophysiology 2002; 19(5):461-468.
- Boon P, Vonck K, Van Walleghem P, D’ Have M, Caemaert J, De Reuck J. Vagus nerve stimulation for epilepsy, clinical efficacy of programmed and magnet stimulation. Acta Neurochirurgica 2002; 79(suppl.):93-9.
- Boon P, Pevernagie D, Schrans D. Hypersomnolence and narcolepsy; a pragmatic diagnostic neurophysiological approach. Acta Neurologica Belgica 2002; 102:11-18.
- Boon P, Chauvel P, Pohlman-Eden B, Outol C, Wroe S. Dose-response effect of levetiracetam 1000 and 2000 mg/day in partial epilepsy. Epilepsy Research 2002; 48:77-89.
- Boon P, D’have M, Van Walleghem P, Michielsen G, Vonck K, Caemaert J, De Reuck J. Direct medical costs of refractory epilepsy incurred by three different treatment modalities: a prospective assessment. Epilepsia 2002; 43:96-103.
- Boon P.A.J.M., Vonck K., De Reuck J., Caemaert J. Vagus nerve stimulation for refractory epilepsy, case reports. Seizure 2001;10:456-460
- Boon P.A.J.M., Vonck K., De Reuck J., Caemaert J. Vagus nerve stimulation for refractory epilepsy. Seizure 2001;10:448-455
- Boon P.A.J.M., Vonck K., Van Walleghem P., D’Have M., Goossens L., Vandekerckhove T., Caemaert J., De Reuck J. Programmed and magnet-induced vagus nerve stimulation for refractory epilepsy. J Clin Neurophysiol 2001;18:402-407
- Boon P.A.J.M., Vonck K., Vandekerckhove T., De Reuck J., Calliauw L. Vagus nerve stimulation for refractory epilepsy. Neurosurgery Quarterly 2001;11:66-72
- Bomer N, Boon P, Brennand M. Epilepsiecentrum Kempenhaeghe. Kempenhaeghe Epilepsy Centre. Seizure 2003; 12:23-26
- Aldenkamp AP, Boon PA, Deblaere K, Achten E, Backes WH, Boon P, Hofman P, Troost J, Vandemaele P, Vermeulen J, Vonck K, Wilmink J. Usefulness of language and memory testing during intracarotid amobarbital testing; observations from a fMRI study. Acta Neurologica. Acta Neurologica Scandinavica 2003; 108:147-152.
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