Onderzoekers
dr.ir. J.A.R.J. Hulsman
klinisch chemicus
Functie in Kempenhaeghe:
klinisch chemicus, hoofd van Klinisch-Chemisch Laboratorium, coördinator onderzoeksgroep 'Safety of antiepileptic drugs' , lid commissie Onderzoek & Ontwikkeling, voorzitter Medisch Ethische Toetsings Commissie Kempenhaeghe (pensionering 2010)
Specialisme:
Epileptologie
Wetenschappelijke publicaties
- Vagus Nerve Stimulation in Refractory Epilepsy: Effects on Pro- and Anti-Inflammatory Cytokines in Peripheral Blood. Majoie HJ, Rijkers K, Berfelo MW, Hulsman JA, Myint A, Schwarz M, Vles JS. Neuroimmunomodulation. 2011;18(1):52-6. Epub 2010 Jul 17. PMID: 20639683 [PubMed - indexed for MEDLINE]
- Blood beta-hydroxybutyrate correlates better with seizure reduction due to ketogenic diet than do ketones in the urine. van Delft R, Lambrechts D, Verschuure P, Hulsman J, Majoie M. Seizure. 2010 Jan;19(1):36-9. Epub 2009 Dec 3. PMID: 19962324 [PubMed - indexed for MEDLINE]
- Blood beta-hydroxybutyrate correlates better with seizure reduction due to ketogenic diet than do ketones in the urine. van Delft R, Lambrechts D, Verschuure P, Hulsman J, Majoie M. Seizure. 2010 Jan;19(1):36-9. Epub 2009 Dec 3. PMID: 19962324 [PubMed - indexed for MEDLINE]
- The impact of side effects on long-term retention in three new antiepileptic drugs Bootsma HP, Ricker L, Hekster YA, Hulsman J, Lambrechts D, Majoie M, Schellekens A, de Krom M, Aldenkamp AP. Seizure. 2009 Jun;18(5):327-31. Epub 2008 Dec 24. PMID: 19110447 [PubMed - indexed for MEDLINE]
- The impact of side effects on long-term retention in three new antiepileptic drugs Bootsma HP, Ricker L, Hekster YA, Hulsman J, Lambrechts D, Majoie M, Schellekens A, de Krom M, Aldenkamp AP. Seizure. 2009 Jun;18(5):327-31. Epub 2008 Dec 24. PMID: 19110447 [PubMed - indexed for MEDLINE]
- Long-term effects of levetiracetam and topiramate in clinical practice: A head-to-head comparison. Bootsma HP, Ricker L, Diepman L, Gehring J, Hulsman J, Lambrechts D, Leenen L, Majoie M, Schellekens A, de Krom M, Aldenkamp AP. Seizure. 2008 Jan;17(1):19-26. Epub 2007 Jul 6. PMID: 17618131 [PubMed - indexed for MEDLINE]
- Lamotrigine in clinical practice: long-term experience in patients with refractory epilepsy referred to a tertiary epilepsy center. Bootsma HP, Vos AM, Hulsman J, Lambrechts D, Leenen L, Majoie M, Savelkoul M, Schellekens A, Aldenkamp AP. Epilepsy Behav. 2008 Feb;12(2):262-8. PMID: 18093878 [PubMed - indexed for MEDLINE]
- Lamotrigine in clinical practice: Long-term experience in patients with refractory epilepsy referred to a tertiary epilepsy center. Epilepsy Behav. 2007 Dec 17; [Epub ahead of print] PMID: 18093878 Bootsma HP, Vos AM, Hulsman J, Lambrechts D, Leenen L, Majoie M, Savelkoul M, Schellekens A, Aldenkamp AP.
- Long-term effects of levetiracetam and topiramate in clinical practice: A head-to-head comparison. Seizure. 2007 Jul 5; [Epub ahead of print] PMID: 17618131 [PubMed - as supplied by publisher] Bootsma HP, Ricker L, Diepman L, Gehring J, Hulsman J, Lambrechts D, Leenen L, Majoie M, Schellekens A, de Krom M, Aldenkamp AP.
- Bootsma HP, Ricker L, Diepman L, Gehring J, Hulsman J, Lambrechts D, Leenen L, Majoie M, Schellekens A, de Krom M, Aldenkamp AP. - Levetiracetam in clinical practice: Long-term experience in patients with refractory epilepsy referred to a tertiary epilepsy center. Epilepsy Behav. 2007 Feb 19; [Epub ahead of print] PMID: 17317325 [PubMed - as supplied by publisher]
- Bootsma HP, Aldenkamp AP, Diepman L, Hulsman J, Lambrechts D, Leenen L, Majoie M, Schellekens A, de Krom M. The Effect of Antiepileptic Drugs on Cognition: Patient Perceived Cognitive Problems of Topiramate versus Levetiracetam in Clinical Practice. Epilepsia. 2006 Nov;47(s2):24-27. PMID: 17105455
- HP Bootsma, F Coolen, AP Aldenkamp, J Arends, L Diepman, J Hulsman, D Lambrechts, L Leenen, M Majoie, A Schellekens, M de Krom. Topiramate in clinical practice: long-term experience in patients with refractory epilepsy referred to a tertiary epilepsy center. Epilepsy Behav. 2004 Jun;5(3):380-7.
- Aldenkamp AP, Arends J, Bootsma HP, Diepman L, Hulsman J, Lambrechts D, Leenen L, Majoie M, Schellekens A, de Vocht J. Randomized Double-blind Parallelgroup Study Comparing Cognitive Effects of a Low-dose Lamotrigine with Valproate and Placebo in Healthy Volunteers. Epilepsia 2002; 43(1):19-26.
- Aldenkamp A.P., Arends J.B.A.M., Bootsma H.P., Diepman L., Hulsman J.A.R.J., Lambrechts D.A.J.E., Leenen L., Majoie H.J.M., Schellekens A., de Vocht J. Randomized Double-blind Parallel-group Study Comparing Cognitive Effects of a Low-dose Lamotrigine with Valproate and Placebo in Healthy Volunteers. Epilepsia. 2002 Jan;43(1):19-26.
Betrokken bij de volgende onderzoeken
- Het gebruik van de nieuwere anti-epileptica bij refractaire patiënten
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